A non-selective COX inhibitor
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Eltenac

Item No. 27673

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(2,6-dichlorophenyl)amino]-3-thiopheneacetic acid
CAS Number
72895-88-6
Molecular Formula
C12H9Cl2NO2S
Formula Weight
302.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleMethanol: soluble
SMILES
ClC1=C(NC2=CSC=C2CC(O)=O)C(Cl)=CC=C1
InChi Code
InChI=1S/C12H9Cl2NO2S/c13-8-2-1-3-9(14)12(8)15-10-6-18-5-7(10)4-11(16)17/h1-3,5-6,15H,4H2,(H,16,17)
InChi Key
AELILMBZWCGOSB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $169

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    1 mg

    $319

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    5 mg

    $1,003

    Add
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    Product Description

    Eltenac is a non-selective COX inhibitor (IC50 = 0.03 µM for both COX-1 and COX-2 in isolated human whole blood) and a non-steroidal anti-inflammatory drug (NSAID).1 In vivo, eltenac (1 mg/kg) reduces lameness in horses with tendinitis, pododermatitis, navicular disease, non-infectious arthritis, degenerative joint disease, phalanx fracture, and osteochondrosis.2 It also reduces castration-induced edema in horses. Formulations containing eltenac have been used in the treatment of postoperative swelling in horses.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Klein, T., Dullweber, F., Brehm, C., et al. Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo. Biochem. Pharmacol. 76(6), 717-725 (2008).

    2. Prügner, W., Huber, R., and Lühmann, R. Eltenac, a new anti-inflammatory and analgesic drug for horses: clinical aspects. J. Vet. Pharmacol. Ther. 14(2), 193-199 (1991).