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Guanosine is a purine nucleoside that is comprised of the purine base guanine attached to a ribose moiety.1 Mono-, di-, tri-, and cyclic monophosphorylated forms of guanosine (GMP, GDP, GTP, and cGMP, respectively) are essential for a variety of endogenous biochemical processes, such as signal transduction, metabolism, and RNA synthesis.2,3,4
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1. Biochemistry. 1591 (2004).
2. Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis. Am. J. Clin. Nutr. 25(10), 1010-1021 (1972).
3. G proteins: Critical control points for transmembrane signals. Protein Sci. 3(1), 3-14 (1994).
4. The role of guanosine 5'-