An antibiotic and swine growth regulator
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Active Metabolite(s)
256643-Methylquinoxaline-2-carboxylic Acid
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Olaquindox

Item No. 27725

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide
CAS Number
23696-28-8
Synonyms
  • NSC 634933
Molecular Formula
C12H13N3O4
Formula Weight
263.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
λmax
231, 268, 385 nm
SMILES
[O-][N+]1=C(C(NCCO)=O)C(C)=[N+]([O-])C2=C1C=CC=C2
InChi Code
InChI=1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)
InChi Key
TURHTASYUMWZCC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

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    500 mg

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    Cayman Chemical
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    Product Description

    Olaquindox is an antibiotic and a swine growth regulator.1 In vivo, olaquindox (100 mg/kg) decreases E. coli-induced diarrhea and the number of intraepithelial lymphocytes in the ileum and increases body weight in geld piglets. Olaquindox induces bleeding, intramuscular edema, vacuolar degeneration, and deformation of renal tubules in C. carpio.2 It decreases mean body weight and increases the number of dead fetuses in pregnant rats when administered at a dose of 110 mg/kg and increases the number of external deformities, including bent tail, craniorachischisis, exencephaly, and anophthalmia in rat pups born to exposed pregnant mothers.3 Formulations containing olaquindox have been used as growth promoting agents in bovine livestock.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ding, M.X., Yuan, Z.H., Wang, Y.L., et al. Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunity of piglets orally inoculated with Escherichia coli. J. Anim. Physiol. Anim. Nutr. (Berl.) 90(5-6), 238-243 (2006).

    2. Ye, C., Wang, E., He, S., et al. Subchronic toxicity and hepatocyte apoptosis of dietary olaquindox in common carp (Cyprinus carpio). Ecotoxicol. Environ. Saf. 164, 131-139 (2018).

    3. Kang, H.G., Ku, H.O., Jeong, S.H., et al. Evaluation of embryotoxic potential of olaquindox and vitamin A in micromass culture and in rats. Toxicol. Res. 26(3), 209-216 (2010).