A polyether antibiotic
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Martinomycin

Item No. 27737

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(αR,2S,3S,4S,5S,6S)-6-[[(2R,3R,4R,5S,7S,9R,10R)-3,9-dimethoxy-2,4,10-trimethyl-2-[(2S,2'R,5R,5'R)-octahydro-5'-[(2S,3S,4S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-α,3,5-trimethyl-2H-pyran-2-acetic acid
CAS Number
160791-16-2
Synonyms
  • LL-D 37187α
Molecular Formula
C49H84O17
Formula Weight
945.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleEthanol: solubleMethanol: soluble
SMILES
OC([C@H](C)[C@@]1(O)O[C@](C[C@@H](O2)C[C@@H](OC)[C@@H](C)[C@@]32[C@H](C)[C@@H](OC)[C@]([C@@]4([H])CC[C@]([C@@]5([H])CC[C@@]([C@]6([H])[C@@H](C)[C@H](O[C@@]7([H])CC[C@H](OC)[C@@H](C)O7)[C@@H](C)[C@](O)(C)O6)([H])O5)([H])O4)(C)O3)([H])[C@@](OC)(C)[C@@H](OC)[C@@H]1C)=O
InChi Code
InChI=1S/C49H84O17/c1-24-40(62-39-21-19-32(54-11)30(7)59-39)26(3)47(10,52)65-41(24)35-17-16-33(60-35)34-18-20-37(61-34)46(9)43(57-14)28(5)49(66-46)25(2)36(55-12)22-31(63-49)23-38-45(8,58-15)42(56-13)27(4)48(53,64-38)29(6)44(50)51/h24-43,52-53H,16-23H2,1-15H3,(H,50,51)/t24-,25+,26+,27-,28+,29-,30+,31-,32-,33+,34-,35+,36+,37+,38-,39-,40-,41-,42-,43+,45-,46+,47-,48-,49-/m0/s1
InChi Key
VIAPPZHHJMCDEJ-JXBMCXTESA-N
Origin
Bacterium/Actinoallamurus yoronensis
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Martinomycin is a polyether antibiotic originally isolated from the actinomycete S. salvialis.1,2 It is active against a variety of bacteria, including 11 strains of S. aureus, three strains of S. pneumoniae, and E. faecalis (MICs = 0.12-0.5, 0.06, and 0.5 µg/ml, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Carter, G.T., Schlingmann, G., Kenion, G.B., et al. Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. II. Isolation and structure determination. J. Antibiot. (Tokyo) 47(12), 1549-1553 (1994).

    2. Bernan, V.S., Montenegro, D.A., Goodman, J.J., et al. Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. I. Taxonomy, fermentation and biological activity. J. Antibiot. (Tokyo) 47(12), 1434-1441 (1994).