A detergent used to solubilize membrane proteins
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Biochemicals
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DDTAC

Item No. 27741

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N1,N3,N5,N7,N9,N11-hexakis(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-12-(dodecylthio)dodecane-1,3,5,7,9,11-hexacarboxamide
Synonyms
  • Dodecylmercapto-S-(poly(tris(hydroxymethyl)acrylamidomethane)
  • H12-TAC
Purity
≥85%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
SMILES
[H]C(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CSCCCCCCCCCCCC
InChi Code
InChI=1S/C54H104N6O24S/c1-2-3-4-5-6-7-8-9-10-11-14-85-19-42(48(84)60-54(35-76,36-77)37-78)18-41(47(83)59-53(32-73,33-74)34-75)17-40(46(82)58-52(29-70,30-71)31-72)16-39(45(81)57-51(26-67,27-68)28-69)15-38(44(80)56-50(23-64,24-65)25-66)12-13-43(79)55-49(20-61,21-62)22-63/h38-42,61-78H,2-37H2,1H3,(H,55,79)(H,56,80)(H,57,81)(H,58,82)(H,59,83)(H,60,84)
InChi Key
RJISIWGNYMJWEH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $277

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    Product Description

    DDTAC is a detergent used to solubilize membrane proteins.1 It has a critical micelle concentration (CMC) of approximately 0.15 mM. DDTAC has been used to extract yeast ATP synthase from mitochondrial membranes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Talbot, J.-C., Dautant, A., Polidori, A., et al. Hydrogenated and fluorinated surfactants derived from Tris(hydroxymethyl)-acrylamidomethane allow the purification of a highly active yeast F1-F0 ATP-synthase with an enhanced stability. J. Bioenerg. Biomembr. 41(4), 349-360 (2009).