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Pagoclone

Item No. 27749

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • RP 59037
Technical Information
Formal Name
2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-(5-methyl-2-oxohexyl)-1H-isoindol-1-one
CAS Number
133737-48-1
Molecular Formula
C23H22ClN3O2
Formula Weight
407.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: insolEthanol: insolPBS (pH 7.2): insol
SMILES
ClC1=CC=C(C=CC(N2C(CC(CCC(C)C)=O)C3=C(C=CC=C3)C2=O)=N4)C4=N1
InChi Code
InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChi Key
HIUPRQPBWVEQJJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Pagoclone (Item No. 27749) is an analytical reference standard categorized as a cyclopyrrolone.1 Pagoclone has anxiolytic-like, anticonvulsant, and anti-aggressive activities in rodents. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Doble, A., Canton, T., Piot, D.O., et al. RP 59037 and RP 60503: Anxiolytic cyclopyrrolone derivatives with low sedative potential. Interaction with the γ-aminobutyric acidA/benzodiazepine receptor complex and behavioral effects in the rodent. J. Pharmacol. Exp. Ther. 266(3), 1213-1226 (1993).