An amine-reactive fluorescent probe
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BODIPY 630/650X succinimide ester

Item No. 27758

Technical Information
Formal Name
(T-4)-[2,5-dioxo-1-pyrrolidinyl 6-[[2-[4-[2-[5-[[5-(2-thienyl)-2H-pyrrol-2-ylidene-κN]methyl]-1H-pyrrol-2-yl-κN]ethenyl]phenoxy]acetyl]amino]hexanoato]difluoro-boron
CAS Number
380367-48-6
Synonyms
  • BODIPY 630/650X SE
Molecular Formula
C33H31BF2N4O6S
Formula Weight
Purity
≥90%
Emission
650 nm
Excitation
630 nm
A solid
Methanol: soluble
λmax
628 nm
SMILES
[F][B-]1([N+]2=C(C3=CC=CS3)C=CC2=CC4=CC=C(/C=C/C5=CC=C(OCC(NCCCCCC(ON6C(CCC6=O)=O)=O)=O)C=C5)[N]14)[F]
InChi Code
InChI=1S/C33H31BF2N4O6S/c35-34(36)38-24(11-12-25(38)21-26-13-16-28(39(26)34)29-5-4-20-47-29)10-7-23-8-14-27(15-9-23)45-22-30(41)37-19-3-1-2-6-33(44)46-40-31(42)17-18-32(40)43/h4-5,7-16,20-21H,1-3,6,17-19,22H2,(H,37,41)/b10-7+
InChi Key
TZBGLTNFAMQEEZ-JXMROGBWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    BODIPY 630/650X succinimide ester (SE) is an amine-reactive fluorescent probe that contains an integrated aminohexanoyl linker (X).1,2 It displays excitation/emission maxima of 630/650 nm, respectively. BODIPY 630/650X SE has been used, linked to adenosine A1 receptor ligands, as a fluorescent probe to quantify ligand-receptor binding using fluorescence correlation spectroscopy.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Briddon, S.J., Middleton, R.J., Cordeaux, Y., et alQuantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells. Proc. Natl. Acad. Sci. USA 101(13), 4673-4678 (2004).

    2. Dale, C.L., Hill, S.J., and Kellam, B. New potent, short-linker BODIPY-630/650™ labelled fluorescent adenosine receptor agonists. Med. Chem. Commun. 3(3), 333-338 (2012).