A medium-chain acyl CoA
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Octanoyl-Coenzyme A (sodium salt)

Item No. 27868

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
S-octanoate coenzyme A, sodium salt
Synonyms
  • Octanoyl-CoA
Molecular Formula
C29H50N7O17P3S • XNa
Formula Weight
893.7
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: Partially solublePBS (pH 7.2): 10 mg/ml
SMILES
O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCCCCC)=O)=O)=O)(O)=O)(O)=O)[C@H]1OP(O)(O)=O.[Na]
InChi Code
InChI=1S/C29H50N7O17P3S.Na/c1-4-5-6-7-8-9-20(38)57-13-12-31-19(37)10-11-32-27(41)24(40)29(2,3)15-50-56(47,48)53-55(45,46)49-14-18-23(52-54(42,43)44)22(39)28(51-18)36-17-35-21-25(30)33-16-34-26(21)36;/h16-18,22-24,28,39-40H,4-15H2,1-3H3,(H,31,37)(H,32,41)(H,45,46)(H,47,48)(H2,30,33,34)(H2,42,43,44);/t18-,22-,23-,24+,28-;/m1./s1
InChi Key
APEGDHAYYMKUJF-QGYZRCADSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $41

    Add

    5 mg

    $178

    Add

    10 mg

    $312

    Add

    25 mg

    $680

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Octanoyl-coenzyme A (octanoyl-CoA) is a medium-chain acyl CoA and a metabolic intermediate in mitochondrial fatty acid β-oxidation.1,2,3 Levels of octanoyl-CoA are increased in the liver of patients with Reye’s syndrome and β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH) is decreased in patients with MCADH deficiency (MCD).2,3 Octanoyl-CoA inhibits citrate synthase and glutamate dehydrogenase.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lai, J.C., Liang, B.B., Jarvi, E.J., et al. Differential effects of fatty acyl coenzyme A derivatives on citrate synthase and glutamate dehydrogenase. Res. Commun. Chem. Pathol. Pharmacol. 82(3), 331-338 (1993).

    2. Corkey, B.E., Hale, D.E., Glennon, M.V., et al. Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome. J. Clin. Invest. 82(3), 782-788 (1988).

    3. Amendt, B.A., and Rhead, W.J. Catalytic defect of medium-chain acyl-coenzyme A dehydrogenase deficiency. Lack of both cofactor responsiveness and biochemical heterogeneity in eight patients. J. Clin. Invest. 76(3), 963-969 (1985).