An internal standard for the quantification of sphingosine (d18:1)
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Sphingosine-13C2-d2 (d18:1)

Item No. 27875

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,3R,4E)-2-amino-4-octadecene-1,1-d2-1,3-diol-1,2-13C2
CAS Number
2692623-81-5
Synonyms
  • D-erythro-Sphingosine C18-13C2-d2
Molecular Formula
C16[13C]2H35D2NO2
Formula Weight
303.5
Purity
≥99% deuterated forms (d1-d2)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: solubleMethanol: soluble
SMILES
O[13C]([2H])([2H])[13C@H](N)[C@H](O)/C=C/CCCCCCCCCCCCC
InChi Code
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1/i16+1D2,17+1
InChi Key
WWUZIQQURGPMPG-IMIVUYSRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    Sphingosine-13C2-d2 (d18:1) is intended for use as an analytical standard for the quantification of sphingosine (d18:1) (Item No. 10007907) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.1 Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.1 Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.2,3,4

    WARNING This product is not for human or veterinary use.