A microcide
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Povidone-Iodine

Item No. 27883

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-ethenyl-2-pyrrolidinone, homopolymer, compd. with iodine
CAS Number
25655-41-8
Synonyms
  • Iodopovidone
  • NSC 26245
  • Polyvinylpyrrolidone-Iodine
Molecular Formula
(C6H9NO)n •XI2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleWater: Soluble
SMILES
O=C1CCCN1C(C)CC.II
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 g

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    Cayman Chemical
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    Product Description

    Povidone-iodine is a microcide with broad-spectrum activity against bacteria, fungi, viruses, and protozoans.1 It reduces total anaerobic and aerobic bacterial counts in vitro in dog feces when applied topically as a 10% solution.2 Povidone-iodine decreases bacterial counts and the occurrence of anastomotic leaks in a dog model of emergent resection and anastomosis of the sigmoid colon when applied in situ at a concentration of 10% v/v. Topical administration of povidone-iodine (10% v/v) also reduces bacterial counts on the skin of cynomolgus monkeys.3 Formulations containing povidone-iodine have been used to disinfect skin before and after surgery.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Eggers, M., Eickmann, M., Kowalski, K., et al. Povidone-iodine hand wash and hand rub products demonstrated excellent in vitro virucidal efficacy against Ebola virus and modified vaccinia virus Ankara, the new European test virus for enveloped viruses. BMC Infect. Dis. 15:375, (2015).

    2. Jones, F.E., DeCosse, J.J., and Condon, R.E. Evaluation of "instant" preparation of the colon with povidone-iodine. Ann. Surg. 184(1), 74-79 (1976).

    3. Nakata, H., Tsubotani, Y., Nii, T., et al. Effects of olanexidine gluconate on preoperative skin preparation: An experimental study in cynomolgus monkeys. J. Med. Microbiol. 66(5), 678-685 (2017).