A fungal metabolite
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(+)-Quinolactacin A1

Item No. 27939

Technical Information
Formal Name
(3R)-2,3-dihydro-4-methyl-3-[(1S)-1-methylpropyl]-1H-pyrrolo[3,4-b]quinoline-1,9(4H)-dione
CAS Number
815576-68-2
Molecular Formula
C16H18N2O2
Formula Weight
Purity
≥95%
Formulation
A solid
Methanol: Slightly Soluble: 0.1-1 mg/ml
SMILES
O=C1C2=C([C@]([C@H](CC)C)([H])NC2=O)N(C)C3=C1C=CC=C3
InChi Code
InChI=1S/C16H18N2O2/c1-4-9(2)13-14-12(16(20)17-13)15(19)10-7-5-6-8-11(10)18(14)3/h5-9,13H,4H2,1-3H3,(H,17,20)/t9-,13+/m0/s1
InChi Key
FLHQAMWKNPOTDV-TVQRCGJNSA-N
Origin
Fungus/Penicillium citrinum
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    (+)-Quinolactacin A1 is a fungal metabolite originally isolated from P. citrinum. It inhibits acetylcholinesterase (AChE) in vitro (IC50 = 280 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kim, W.-G., Song, N.-K., and Yoo, I.-D. Quinolactacins A1 and A2, new acetylcholinesterase inhibitors from Penicillium citrinum. J. Antibiot. (Tokyo) 54(10), 831-835 (2001).