A flavonoid C-glycoside with diverse biological activities
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Schaftoside

Item No. 27950

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8-α-L-arabinopyranosyl-6-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number
51938-32-0
Synonyms
  • Apigenin 6-C-glucoside-8-C-arabinoside
Molecular Formula
C26H28O14
Formula Weight
564.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
λmax
217, 274, 335 nm
SMILES
OC1=C([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C(O)=C(C(C=C(C3=CC=C(O)C=C3)O4)=O)C4=C1[C@@H]5OC[C@H](O)[C@H](O)[C@H]5O
InChi Code
InChI=1S/C26H28O14/c27-6-13-18(32)21(35)23(37)26(40-13)15-19(33)14-10(29)5-12(8-1-3-9(28)4-2-8)39-24(14)16(20(15)34)25-22(36)17(31)11(30)7-38-25/h1-5,11,13,17-18,21-23,25-28,30-37H,6-7H2/t11-,13+,17-,18+,21-,22+,23+,25-,26-/m0/s1
InChi Key
MMDUKUSNQNWVET-VYUBKLCTSA-N
Origin
Plant/Desmodium styracifolium
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $51

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    5 mg

    $241

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    10 mg

    $456

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    25 mg

    $948

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    Cayman Chemical
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    Product Description

    Schaftoside is a flavonoid C-glycoside that has been found in C. annum and has antioxidant and anti-inflammatory activities.1,2 It inhibits xanthine oxidase with an IC50 value of 51.4 μM and has antioxidant activity in a β-carotene-linoleic acid bleaching assay (IC50 = 46.3 μM).1 Schaftoside (400 μg/kg) inhibits neutrophil influx into mouse lung by 62% in a model of airway inflammation induced by aerosol administration of LPS.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Materska, M. Flavone C-glycosides from Capsicum annuum L.: Relationships between antioxidant activity and lipophilicity. Eur. Food Res. Technol. 240(3), 549-557 (2015).

    2. De Melo, G.O., Muzitano, M.F., Legora-Machado, A., et al. C-Glycosylflavones from the aerial parts of Eleusine indica inhibit LPS-induced mouse lung inflammation. Planta Med. 71(4), 362-363 (2005).