A peptide fragment of histone H3
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Histone H3 (5-23) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Item No. 28048

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • QTARKSTGGKAPRKQLATK
Molecular Formula
C85H155N31O26 • XCF3COOH
Formula Weight
2027.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
[H]N[C@@H](CCC(N)=O)C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@]([C@@H](C)O)([H])C(NCC(NCC(N[C@@H](CCCCN)C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCN)C(O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C85H155N31O26.C2HF3O2/c1-42(2)38-57(76(134)101-44(4)68(126)113-66(48(8)120)81(139)110-56(83(141)142)23-12-16-34-89)111-75(133)55(28-30-61(92)122)108-71(129)51(21-10-14-32-87)106-73(131)54(25-18-36-98-85(95)96)109-78(136)59-26-19-37-116(59)82(140)45(5)103-70(128)50(20-9-13-31-86)104-63(124)40-99-62(123)39-100-79(137)64(46(6)118)115-77(135)58(41-117)112-74(132)52(22-11-15-33-88)107-72(130)53(24-17-35-97-84(93)94)105-67(125)43(3)102-80(138)65(47(7)119)114-69(127)49(90)27-29-60(91)121;3-2(4,5)1(6)7/h42-59,64-66,117-120H,9-41,86-90H2,1-8H3,(H2,91,121)(H2,92,122)(H,99,123)(H,100,137)(H,101,134)(H,102,138)(H,103,128)(H,104,124)(H,105,125)(H,106,131)(H,107,130)(H,108,129)(H,109,136)(H,110,139)(H,111,133)(H,112,132)(H,113,126)(H,114,127)(H,115,135)(H,141,142)(H4,93,94,97)(H4,95,96,98);(H,6,7)/t43-,44-,45-,46+,47+,48+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,64-,65-,66-;/m0./s1
InChi Key
WTGMOEAWDYBSHV-PEJYNSRWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $303

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    Product Description

    Histone H3 (5-23) is a peptide fragment of histone H3 that corresponds to amino acid residues 6-24 of the human histone H3.3 sequence. Histone H3 contains a lysine residue at position 14 that is subject to acetylation and has a role in transcriptional activation and regulation of gene expression.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Holbert, M.A., Sikorski, T., Carten, J., et al. The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting. The Journal of Biological Chemisty 282(50), 36603-36613 (2007).

    2. Karmodiya, K., Krebs, A.R., Oulad-Abdelghani, M., et al. H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells. BMC Genomics 13:424, (2012).