A peptide fragment of histone H3
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Histone H3 (69-89) amide (human, mouse, rat, bovine) (trifluoroacetate salt)

Item No. 28146

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-arginyl-L-leucyl-L-valyl-L-arginyl-L-glutamyl-L-isoleucyl-L-alanyl-L-glutaminyl-L-aspartyl-L-phenylalanyl-L-lysyl-L-threonyl-L-aspartyl-L-leucyl-L-arginyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-seryl-L-alanyl-L-valinamide, trifluoroacetate salt
Synonyms
  • RLVREIAQDFKTDLRFQSSAV-NH2
Molecular Formula
C109H180N34O32 • XCF3COOH
Formula Weight
2478.8
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
O=C(O)C(F)(F)F.NC([C@H](C(C)C)NC([C@@H](NC([C@H](CO)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCCCN)NC([C@@H](NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](NC([C@@]([C@H](CC)C)([H])NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)N[H])=O)=O)=O)=O)=O)=O)C)=O)=O)CC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC(O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)C)=O)=O
InChi Code
InChI=1S/C109H180N34O32.C2HF3O2/c1-14-56(10)84(142-95(164)68(36-39-79(149)150)129-90(159)65(33-25-43-123-109(119)120)131-104(173)83(55(8)9)141-101(170)70(45-53(4)5)132-89(158)62(111)30-23-41-121-107(115)116)105(174)125-57(11)87(156)126-66(34-37-77(112)147)92(161)136-73(48-80(151)152)99(168)135-72(47-61-28-19-16-20-29-61)97(166)127-63(31-21-22-40-110)94(163)143-85(59(13)146)106(175)137-74(49-81(153)154)100(169)133-69(44-52(2)3)96(165)128-64(32-24-42-122-108(117)118)91(160)134-71(46-60-26-17-15-18-27-60)98(167)130-67(35-38-78(113)148)93(162)138-76(51-145)103(172)139-75(50-144)102(171)124-58(12)88(157)140-82(54(6)7)86(114)155;3-2(4,5)1(6)7/h15-20,26-29,52-59,62-76,82-85,144-146H,14,21-25,30-51,110-111H2,1-13H3,(H2,112,147)(H2,113,148)(H2,114,155)(H,124,171)(H,125,174)(H,126,156)(H,127,166)(H,128,165)(H,129,159)(H,130,167)(H,131,173)(H,132,158)(H,133,169)(H,134,160)(H,135,168)(H,136,161)(H,137,175)(H,138,162)(H,139,172)(H,140,157)(H,141,170)(H,142,164)(H,143,163)(H,149,150)(H,151,152)(H,153,154)(H4,115,116,121)(H4,117,118,122)(H4,119,120,123);(H,6,7)/t56-,57-,58-,59+,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,82-,83-,84-,85-;/m0./s1
InChi Key
ZATQOOKBOVKIGM-IWOGIHCJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $334

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    Product Description

    Histone H3 (69-89) amide is a peptide fragment of histone H3 that corresponds to amino acid residues 70-90 of the human histone H3.1 and H3.2 sequences. Histone H3 (69-89) amide contains a lysine residue at position 79 that is subject to methylation and acetylation and has a role in regulation of gene expression.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Garcia, B.A., Hake, S.B., Diaz, R.L., et al. Organismal differences in post-translational modifications in histones H3 and H4. The Journal of Biological Chemisty 282(10), 7641-7655 (2007).

    2. Barski, A., Cuddapah, S., Cui, K., et al. High-resolution profiling of histone methylations in the human genome. Cell 129(4), 823-837 (2007).