An internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE
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1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE

Item No. 28155

Technical Information
Formal Name
(2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl hexadecanoate-13,13,14,14,15,15,16,16,16-d9
CAS Number
2747990-85-6
Synonyms
  • 16:0-d9/16:0-PE
  • 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine
  • 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine
  • PE(16:0-d9/16:0)
Molecular Formula
C37H65D9NO8P
Formula Weight
Purity
≥99% deuterated forms (d1-d9)
Formulation
A1 mg/ml solution of chloroform:methanol (2:1)
Chloroform: 1 mg/ml
SMILES
O=C(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])OC[C@@H](OC(CCCCCCCCCCCCCCC)=O)COP(OCC[NH3+])([O-])=O
InChi Code
InChI=1S/C37H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(39)43-33-35(34-45-47(41,42)44-32-31-38)46-37(40)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h35H,3-34,38H2,1-2H3,(H,41,42)/t35-/m1/s1/i1D3,3D2,5D2,7D2
InChi Key
SLKDGVPOSSLUAI-AVFWSPGISA-N
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (Item No. 15092) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally occurring PE containing C16:0 fatty acids at the sn-1 and sn-2 positions. It belongs to a class of phospholipids that are the most abundant lipids in the inner leaflet of the plasma membrane.1 1,2-DPPE interacts with cholesterol to form a condensed lipid monolayer with tight hydrogen bonding of the 1,2-DPPE interheadgroups, resulting in a more fluid membrane that may aid in transport and signaling across the bilayer.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vance, J.E., and Tasseva, G. Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. Biochim. Biophys. Acta 1831(3), 543-554 (2013).

    2. Leekumjorn, S., and Sum, A.K. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys. J. 90(11), 3951-3965 (2006).

    3. McQuaw, C.M., Sostarecz, A.G., Zheng, L., et alLateral heterogeneity of dipalmitoylphosphatidylethanolamine-cholesterol Langmuir-Blodgett films investigated with imaging time-of-flight secondary ion mass spectrometry and atomic force microscopy. Langmuir 21(3), 807-813 (2005).