A fluorescent probe for lipid mono- and bilayers
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1,6-Diphenyl-1,3,5-hexatriene

Item No. 28277

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,1'-(1,3,5-hexatriene-1,6-diyl)bis-benzene
CAS Number
1720-32-7
Synonyms
  • Diphenylhexatriene
  • DPH
  • NSC 90479
Molecular Formula
C18H16
Formula Weight
232.3
Purity
≥98%
Emission
430 nm
Excitation
360 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 0.2mg/mLDMF:PBS (pH 7.2): 0.5mg/mL
λmax
243, 336, 352, 371 nm
SMILES
C1(/C=C/C=C/C=C/C2=CC=CC=C2)=CC=CC=C1
InChi Code
InChI=1S/C18H16/c1(5-11-17-13-7-3-8-14-17)2-6-12-18-15-9-4-10-16-18/h1-16H/b2-1+,11-5+,12-6+
InChi Key
BOBLSBAZCVBABY-WPWUJOAOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    1 g

    $54

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    5 g

    $238

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    Product Description

    1,6-Diphenyl-1,3,5-hexatriene is a probe for lipid mono- and bilayers.1,2,3 It localizes to the hydrocarbon regions in lipid mono- and bilayers and displays excitation/emission maxima of 360/430 nm, respectively.1,2 1,6-Diphenyl-1,3,5-hexatriene has been used to characterize lipid membrane dynamics in vitro and ex vivo and in the determination of the critical micelle concentrations (CMCs) of anionic, cationic, uncharged, and zwitterionic detergents.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chattopadhyay, A., and London, E. Fluorimetric determination of critical micelle concentration avoiding interference from detergent charge. Anal. Biochem. 139(2), 408-412 (1984).

    2. Tang, D., Wieb van der Meer, B., and Simon Chen, S.-Y. Evidence for a regular distribution of cholesterol in phospholipid bilayers from diphenylhexatriene fluorescence. Biophys J. 68(5), 1944-1951 (1995).

    3. Cohen, B.M., and Zubenko, G.S. In vivo effects of psychotropic agents on the physical properties of cell membranes in the rat brain. Psychopharmacology (Berl) 86(3), 365-368 (1985).