A prodrug form of methimazole
Related Products
Active Metabolite(s)
23718Methimazole
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Carbimazole

Item No. 28280

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,3-dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid, ethyl ester
CAS Number
22232-54-8
Molecular Formula
C7H10N2O2S
Formula Weight
186.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1mg/mLDMSO: 1mg/mLEthanol: 1mg/mLEthanol:PBS (pH 7.2) (1:5): 0.10mg/mL
λmax
223, 301, 352, 371 nm
SMILES
CN(C=CN1C(OCC)=O)C1=S
InChi Code
InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
InChi Key
CFOYWRHIYXMDOT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 g

    $63

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    10 g

    $110

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    50 g

    $363

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    100 g

    $662

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    Product Description

    Carbimazole is a prodrug form of the thyroid hormone synthesis inhibitor methimazole (Item No. 23718).1 Carbimazole (15 mg/animal) reduces total thyroxine concentration, thyroid enlargement, polyphagia, anorexia, and alopecia in a cat model of hyperthyroidism.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Frénais, R., Rosenberg, D., Burgaud, S., et al. Clinical efficacy and safety of a once-daily formulation of carbimazole in cats with hyperthyroidism. J. Small Anim. Pract. 50(10), 510-515 (2009).