A fluorescent coumarin derivative
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4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one

Item No. 28474

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-methyl-7-(4-nitrophenoxy)-2H-1-benzopyran-2-one
CAS Number
1644277-00-8
Molecular Formula
C16H11NO5
Formula Weight
297.3
Purity
≥98%
Emission
445 nm
Excitation
323 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: 30 mg/mlDMF: 30 mg/mlDMF:PBS (pH 7.2) (1:2): 0.33 mg/mlDMSO: 5 mg/ml
λmax
317 nm
SMILES
CC(C(C=C1)=C(O2)C=C1OC3=CC=C([N+]([O-])=O)C=C3)=CC2=O
InChi Code
InChI=1S/C16H11NO5/c1-10-8-16(18)22-15-9-13(6-7-14(10)15)21-12-4-2-11(3-5-12)17(19)20/h2-9H,1H3
InChi Key
QRBYWJMPNMMLMY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $128

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    10 mg

    $236

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    25 mg

    $502

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    Product Description

    4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.1,2 It displays excitation/emission maxima of 323/445 nm, respectively.1 Unlike the hydrogen sulfide probe 7-(2,4-dinitrophenoxy)-4-methyl-2H-chromen-2-one (Item No. 28472), 4-methyl-7-(4-nitrophenoxy)-2H-chromen-2-one does not undergo an increase in fluoresence intensity in the presence of sulfur-containing molecules.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, B., Ge, C., Yao, J., et al. Selective selenol fluorescent probes: Design, synthesis, structural determinants, and biological applications. J. Am. Chem. Soc. 137(2), 757-769 (2015).

    2. Chen, Y., Shang, X., Li, C., et al. The synthesis, crystal, hydrogen sulfide detection and cell assement of novel chemsensors based on coumarin derivatives. Sci. Rep. 8(1), 16159 (2018).