An internal standard for the quantification of iohexol
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Unlabeled Version(s)
23753Iohexol
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Iohexol-d5

Item No. 28540

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[acetyl(2,3-dihydroxypropyl-1,1,2,3,3-d5)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS Number
928623-33-0
Molecular Formula
C19H21D5I3N3O9
Formula Weight
826.2
Purity
≥99% deuterated forms (d1-d5)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: slightly solubleWater: slightly soluble
SMILES
IC1=C(C(NCC(O)CO)=O)C(I)=C(N(C(C)=O)C([2H])([2H])C(C([2H])([2H])O)([2H])O)C(I)=C1C(NCC(O)CO)=O
InChi Code
InChI=1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)/i4D2,7D2,11D
InChi Key
NTHXOOBQLCIOLC-OPCJXEHASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $583

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    Product Description

    Iohexol-d5 is intended for use as an internal standard for the quantification of iohexol (Item No. 23753) by GC- or LC-MS. Iohexol is a non-ionic and water-soluble contrast agent.1 It induces inhibition of electrical activity but has no excitatory effect in vitro in rat hippocampal slices and lacks any effect in vivo on ventral root flexes of feline spinal cord, indicating minimal neurotoxicity. Iohexol also induces a smaller decrease in contractile force than the ionic and high osmolarity contrast agent metrizoate in isolated rabbit hearts perfused with a 350 mg/ml solution.2 Formulations containing iohexol have been used for visualization of arteries, veins, the urinary tract, and joints using X-ray and computed tomography (CT) scan imaging techniques.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bryan, R.N., Centeno, R.S., Hershkowitz, N., et al. Neurotoxicity of iohexol: A new nonionic contrast medium. Radiology 145(2), 379-382 (1982).

    2. Almén, T., and Bååth, L. Effects of iopentol, iohexol and metrizoate on the contractility of the isolated rabbit heart. Acta Radiol. Suppl. 370, 61-63 (1987).