A fungal metabolite with vasodilatory activity
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Gymnoascolide A

Item No. 28585

Technical Information
Formal Name
3-phenyl-4-(phenylmethyl)-2(5H)-furanone
CAS Number
865092-05-3
Molecular Formula
C17H14O2
Formula Weight
Purity
≥70%
A solid
Dichloromethane: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
O=C1OCC(CC2=CC=CC=C2)=C1C3=CC=CC=C3
InChi Code
InChI=1S/C17H14O2/c18-17-16(14-9-5-2-6-10-14)15(12-19-17)11-13-7-3-1-4-8-13/h1-10H,11-12H2
InChi Key
RTTHRDSFKNSBAG-UHFFFAOYSA-N
Origin
Fungus/Auxarthron sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Gymnoascolide A is a fungal metabolite that has been found in M. filamentosa and has vasodilatory activity.1 It inhibits calcium-induced contractions in isolated rat aortic rings when used at a concentration of 1 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hosoe, T., Iizuka, T., Komai, S., et al4-Benzyl-3-phenyl-5H-furan-2-one, a vasodilator isolated from Malbranchea filamentosa IFM 41300. Phytochem. 66(23), 2776-2779 (2005).