A compound with anesthetic activity
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Product Type

Biochemicals

Research Area

Neuroscience

NAP-1

Item No. 28719

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(4-chlorophenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid, ethyl ester
CAS Number
131721-28-3
Molecular Formula
C20H18ClNO2
Formula Weight
339.8
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:2): 0.3 mg/mlDMSO: 10 mg/ml
λmax
229, 281 nm
SMILES
CC1=C(C(OCC)=O)C=C(C2=CC=C(Cl)C=C2)N1C3=CC=CC=C3
InChi Code
InChI=1S/C20H18ClNO2/c1-3-24-20(23)18-13-19(15-9-11-16(21)12-10-15)22(14(18)2)17-7-5-4-6-8-17/h4-13H,3H2,1-2H3
InChi Key
RYNBQQWODYCGRR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $36

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    5 mg

    $128

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    10 mg

    $236

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    Product Description

    NAP-1 is a compound with anesthetic activity.1 It increases paired-pulse inhibition in the CA1 region of rat hippocampal brain slices when used at a concentration of 100 μM. NAP-1 also induces loss of righting reflex in tadpoles (EC50 = 0.53 μM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bertaccini, E.J., and Davies, M.F. Novel methods, compounds, and compositions for anesthesia. (2016).