A small molecule inducer of hepatocyte proliferation
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Product Type

Biochemicals

BRD-9424

Item No. 29013

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[[[(5-chloro-2-methoxyphenyl)amino]thioxomethyl]amino]-1-ethyl-1H-pyrazole-3-carboxamide
CAS Number
957485-64-2
Synonyms
  • FPH2
  • Functional Poliferation Hit 2
Molecular Formula
C14H16ClN5O2S
Formula Weight
353.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 15mg/mLDMF:PBS (pH 7.2) (1:4): 0.2mg/mLDMSO: 10mg/mLEthanol: 0.25mg/mL
λmax
275 nm
SMILES
ClC1=CC=C(OC)C(NC(NC2=CN(CC)N=C2C(N)=O)=S)=C1
InChi Code
InChI=1S/C14H16ClN5O2S/c1-3-20-7-10(12(19-20)13(16)21)18-14(23)17-9-6-8(15)4-5-11(9)22-2/h4-7H,3H2,1-2H3,(H2,16,21)(H2,17,18,23)
InChi Key
PCHRYHSDDPPZBV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $90

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    10 mg

    $158

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    25 mg

    $370

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    50 mg

    $696

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    Product Description

    BRD-9424, also known as functional proliferation hit 2 (FPH2), is a small molecule that induces proliferation of primary human hepatocytes in vitro.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shan, J., Schwartz, R.E., Ross, N.T., et al. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat. Chem. Biol. 9(8), 514-520 (2013).