A polyphenol flavonoid
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(±)-Catechin (hydrate)

Item No. 29175

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S)-rel-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, hydrate
Molecular Formula
C15H14O6 • XH2O
Formula Weight
290.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 10 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
279 nm
SMILES
OC1=CC(O)=C(C[C@H](O)[C@@H](C2=CC=C(O)C(O)=C2)O3)C3=C1.O
InChi Code
InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
InChi Key
OFUMQWOJBVNKLR-NQQJLSKUSA-N
Origin
Plant/Green tea
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

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    Product Description

    (±)-Catechin is a polyphenol flavonoid that has been found in C. sinensis leaves and has antioxidant and enzyme inhibitory activities.1,2,3 It reduces iron- and ascorbate-induced lipid peroxidation of isolated bovine brain phospholipid liposomes with an IC50 value of 20 µM in a cell-free assay.2 (±)-Catechin (20 µM) inhibits hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) by 17.7% in an enzyme assay.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, Q., Li, J., Liu, S., et al. A comparative proteomic analysis of the buds and the young expanding leaves of the tea plant (Camellia Sinensis L.). Comparative Study 16(6), 14007-14038 (2015).

    2. Scott, B.C., Butler, J., Halliwell, B., et al. Evaluation of the antioxidant actions of ferulic acid and catechins. Free Radic. Res. Commun. 19(4), 241-253 (1993).

    3. Ahmed-Belkacem, A., Guichou, J.-F., Brillet, R., et al. Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: A new mechanism for antiviral intervention. Nucleic Acids Res. 42(14), 9399-9409 (2014).