An antibiotic and radiosensitizer
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Azomycin

Item No. 29395

Technical Information
Formal Name
2-nitro-1H-imidazole
CAS Number
527-73-1
Synonyms
  • 2-Nitroimidazole
Molecular Formula
C3H3N3O2
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 20 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
215, 316 nm
SMILES
O=[N+](C1=NC=CN1)[O-]
InChi Code
InChI=1S/C3H3N3O2/c7-6(8)3-4-1-2-5-3/h1-2H,(H,4,5)
InChi Key
YZEUHQHUFTYLPH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Azomycin is a nitroimidazole antibiotic and radiosensitizer.1,2 It is active against B. subtilis, M. pyogenes, E. coli, S. dysenteriae, S. paradysenteriae, S. typhi, S. paratyphosa, B. anthracis, M. tuberculosis, and M. phlei in vitro.1 Azomycin enhances radiation-induced cell death in HT-1080, LoVo, and V79-379A cancer cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fattorusso, E., Minale, L., and Sodano, G. Aeroplysinin-1, an antibacterial bromo-compound from the sponge Verongia aerophoba. J. Chem. Soc. Perkin 1 1, 16-18 (1972).

    2. Watts, M.E., Dennis, M.F., and Roberts, I.J. Radiosensitization by misonidazole, pimonidazole and azomycin and intracellular uptake in human tumour cell lines. Int. J. Radiat. Biol. 57(2), 361-372 (1990).