An antimicrobial monohydroxyquinoline
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Chlorquinaldol

Item No. 29396

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,7-dichloro-2-methyl-8-quinolinol
CAS Number
72-80-0
Molecular Formula
C10H7Cl2NO
Formula Weight
228.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 5 mg/ml
SMILES
CC1=NC2=C(C(Cl)=CC(Cl)=C2O)C=C1
InChi Code
InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3
InChi Key
GPTXWRGISTZRIO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

    $44

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    25 g

    $104

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    50 g

    $195

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    Cayman Chemical
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    Product Description

    Chlorquinaldol is a monohydroxyquinoline antimicrobial agent.1 It is active against a variety of fungi (MICs = 1-10 µg/ml), as well as clinical isolates of S. aureus, S. epidermidis, E. faecalis, S. pyogenes, and P. acnes Gram-positive (MICs = 0.016-32 mg/L) and E. coli, P. mirabilis, P. aeruginosa, and Enterobacter Gram-negative bacteria (MICs = 8-512 mg/L).1,2 Chlorquinaldol (100 µg/ml) is also active against clinical isolates of Staphylococcus from bovine mastitis.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Littman, M.L. Antimycotic effect of chlorquinaldol. Trans. N. Y. Acad. Sci. 18(2), 161-174 (1955).

    2. Bortolin, M., Bidossi, A., De Vecchi, E., et al. In vitro antimicrobial activity of chlorquinaldol against microorganisms responsible for skin and soft tissue infections: Comparative evaluation with gentamicin and fusidic acid. Front. Microbiol. 8, 1039 (2017).

    3. Fratta, I., Mann, P.H., and Sigg, E.B. Bacteriophage typing and sensitivity testing to chlorquinaldol of Staphylococci isolated from bovine mastitis. Can. J. Comp. Med. Vet. Sci. 25(4), 96-97 (1961).