A GABA derivative
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Product Categories

Product Type

Biochemicals

Research Area

Neuroscience
Behavioral Neuroscience
Learning & Memory

Picamilon

Item No. 29397

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(3-pyridinylcarbonyl)amino]-butanoic acid
CAS Number
34562-97-5
Synonyms
  • Nicotinoyl-GABA
Molecular Formula
C10H12N2O3
Formula Weight
208.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlDMSO:PBS (pH 7.2) (1:9): 0.10 mg/ml
SMILES
O=C(NCCCC(O)=O)C1=CN=CC=C1
InChi Code
InChI=1S/C10H12N2O3/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14)
InChi Key
NAJVRARAUNYNDX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 mg

    $36

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    250 mg

    $81

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    500 mg

    $153

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    1 g

    $268

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    Product Description

    Picamilon is a derivative of γ-aminobutyric acid (GABA).1 It increases parietal cortical blood flow in rats and rabbits when administered at doses of 50 mg/kg, i.p. and 10 mg/kg, i.v., respectively.2 Picamilon (10 mg/kg) increases latency to enter the dark compartment in the passive avoidance conditioned reflex test in rats compared with control animals, indicating nootropic effects.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kopelevich, V.M., Bulanova, L.N., Grigor'ev, I.A., et al. Synthesis and study of psychotropic and hypotensive properties of new picamilon derivatives. Pharm. Chem. J. 31(10), 536-539 (1997).

    2. Mirzoyan, R.S., Gan'shina, T.S., Kosoi, M.Y., et al. Effect of picamilon on the cerebral cortical blood supply and microcirculation in the pial arteriolar system. Biull. Eksp. Biol. Med. 107(5), 668-670 (1989).