An alkaloid
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Evoxanthine

Item No. 29437

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11-methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one
CAS Number
477-82-7
Synonyms
  • NSC 407812
Molecular Formula
C16H13NO4
Formula Weight
283.3
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
O=C1C2=C(C=C(OCO3)C3=C2OC)N(C)C4=CC=CC=C41
InChi Code
InChI=1S/C16H13NO4/c1-17-10-6-4-3-5-9(10)14(18)13-11(17)7-12-15(16(13)19-2)21-8-20-12/h3-7H,8H2,1-2H3
InChi Key
ULBVHYNIDQSMFC-UHFFFAOYSA-N
Origin
Plant/Evodia alata
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 mg

    $262

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    5 mg

    $976

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    Cayman Chemical
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    Product Description

    Evoxanthine is an alkaloid that has been found in O. renieri and has antimalarial and anticancer activities.1,2 It is active against P. falciparum with an IC50 value of 67.6 µg/ml.1 Evoxanthine decreases proliferation of nine sensitive and drug-resistant cancer cell lines (IC50s = 6.11-80.99 µM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Khalid, S.A., Farouk, A., Geary, T.G., et al. Potential antimalarial candidates from African plants: And in vitro approach using Plasmodium falciparum. J. Ethnopharmacol. 15(2), 201-209 (1986).

    2. Kuete, V., Fouotsa, H., Mbaveng, A.T., et al. Cytotoxicity of a naturally occurring furoquinoline alkaloid and four acridone alkaloids towards multi-factorial drug-resistant cancer cells. Phytomedicine 22(10), 946-951 (2015).