A cholesterol precursor
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14-dehydro Zymostenol

Item No. 29534

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,5α)-cholesta-8,14-dien-3-ol
CAS Number
19431-20-0
Synonyms
  • Δ8,14-Cholestandienol
  • Cholesta-8,14-dien-3β-ol
Molecular Formula
C27H44O
Formula Weight
384.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlEthanol: 2 mg/ml
λmax
250 nm
SMILES
C[C@H](CCCC(C)C)[C@@]1([H])CC=C([C@]1(C)CC2)C3=C2[C@]4(C)[C@](CC3)([H])C[C@@H](O)CC4
InChi Code
InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h12,18-21,23,28H,6-11,13-17H2,1-5H3/t19-,20+,21+,23-,26+,27-/m1/s1
InChi Key
AWBZPJQUWZBRII-CXDHQSPESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $171

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    1 mg

    $325

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    5 mg

    $1,023

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    Product Description

    14-dehydro Zymostenol is a precursor to cholesterol (Item No. 9003100).1 It increases the percentage of myelin basic protein-positive (MBP+) oligodendrocytes formed from oligodendrocyte precursor cells when used at concentrations of 5.8 and 17 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lutsky, B.N., and Schroepfer, G.J., Jr. Studies on the enzymic conversion of 5α-cholesta-8,14-dien-3β-ol to cholesterol. The Journal of Biological Chemisty 245(23), 6449-6455 (1970).

    2. Hubler, Z., Allimuthu, D., Bederman, I., et al. Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination. Nature 560(7718), 372-376 (2018).