A bile acid
Related Products
Parent Compound(s)
200997β-hydroxy Cholesterol
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3β-OH-7-Oxocholenic Acid

Item No. 29541

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β)-3-hydroxy-7-oxo-chol-5-en-24-oic acid
CAS Number
25218-38-6
Synonyms
  • 3β-hydroxy-7-oxo-5-Cholenoic Acid
  • 3β-hydroxy-7-Oxochol-5-enoic Acid
Molecular Formula
C24H36O4
Formula Weight
388.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: 1mg/mLEthanol: 1mg/mLMethanol: 1mg/mL
λmax
238 nm
SMILES
O=C1C=C2C[C@@H](O)CC[C@]2(C)[C@]3([H])[C@]1([H])[C@@](CC[C@]4([H])[C@@H](CCC(O)=O)C)([H])[C@]4(C)CC3
InChi Code
InChI=1S/C24H36O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h13-14,16-19,22,25H,4-12H2,1-3H3,(H,27,28)/t14-,16+,17-,18+,19+,22+,23+,24-/m1/s1
InChi Key
JHFXTNJNQOZGEJ-HICUSVRDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $174

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    1 mg

    $330

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    5 mg

    $1,043

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    Product Description

    3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol (Item No. 20099) in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat. Steroids 15(3), 303-326 (1970).

    2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C. J. Lipid Res. 42(10), 1571-1577 (2001).

    3. Maekawa, M., Omura, K., Sekiguchi, S., et al. Identification of two sulfated cholesterol metabolites found in the urine of a patient with Niemann-Pick disease type C as novel candidate diagnostic markers. Mass Spectrom. (Tokyo) 5(2), S0053 (2016).