An S1P1 receptor agonist
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Phospho-Ginkgolic Acid

Item No. 29638

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-pentadecyl-6-(phosphonooxy)-benzoic acid
CAS Number
2281761-58-6
Synonyms
  • Ginkgolic Acid 2-Phosphate
Molecular Formula
C22H37O6P
Formula Weight
428.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleEthanol: Soluble
λmax
244 nm
SMILES
OP(OC1=C(C(O)=O)C(CCCCCCCCCCCCCCC)=CC=C1)(O)=O
InChi Code
InChI=1S/C22H37O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(21(19)22(23)24)28-29(25,26)27/h15,17-18H,2-14,16H2,1H3,(H,23,24)(H2,25,26,27)
InChi Key
BAQCONCIBGFGAD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $519

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    Product Description

    Phospho-ginkgolic acid is an agonist of sphingosine-1-phosphate receptor 1 (S1P1).1 Phospho-ginkgolic acid (10 μM) induces S1P1 receptor internalization and increases ERK phosphorylation in a concentration-dependent manner in CHO cells expressing S1P1.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Swamy, M.M.M., Murai, Y., Ohno, Y., et al. Structure-inspired design of a sphingolipid mimic sphingosine-1-phosphate receptor agonist from a naturally occurring sphingomyelin synthase inhibitor. Chem. Commun. 54(90), 12758-12761 (2018).