A monoterpene glycoside with diverse biological activities
Related Products
Isomer(s)
19861Paeoniflorin
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Albiflorin

Item No. 29744

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1R,3R,4R,6S,9S)-9-[(benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclo[4.3.0.03,9]nonan-8-one
CAS Number
39011-90-0
Molecular Formula
C23H28O11
Formula Weight
480.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
230 nm
SMILES
O=C1[C@@]2(COC(C3=CC=CC=C3)=O)[C@@](C[C@H]2[C@H](O)C4)(O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@@]4(C)O1
InChi Code
InChI=1S/C23H28O11/c1-21-8-13(25)12-7-23(21,33-19-17(28)16(27)15(26)14(9-24)32-19)22(12,20(30)34-21)10-31-18(29)11-5-3-2-4-6-11/h2-6,12-17,19,24-28H,7-10H2,1H3/t12-,13+,14+,15+,16-,17+,19-,21-,22-,23-/m0/s1
InChi Key
QQUHMASGPODSIW-ICECTASOSA-N
Origin
Plant/Peony
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $129

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    5 mg

    $415

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    10 mg

    $763

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    Product Description

    Albiflorin is a monoterpene glycoside that has been found in P. lactiflora and has diverse biological activities.1,2,3 It prevents increases in reactive oxygen species (ROS), nitrotyrosine, and mitochondrial superoxide levels induced by antimycin A in MC3T3-E1 osteoblastic cells when used at concentrations of 0.1 and 1 μM.1 Albiflorin (50 mg/kg) increases the paw withdrawal threshold and decreases spinal cord levels of IL-1β, IL-6, TNF-α, and chemokine (C-X-C motif) ligand 1 (CXCL1) in rat model of neuropathic pain induced by chronic constriction injury (CCI).2 It decreases the time spent immobile in the forced swim and tail suspension tests in mice when administered at doses of 3.5, 7, and 14 mg/kg, indicating antidepressant-like effects.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Suh, K.S., Choi, E.M., Lee, S.Y., et al. Protective effect of albiflorin against oxidative-stress-mediated toxicity in osteoblast-like MC3T3-E1 cells. Fitoterapia 89, 33-41 (2013).

    2. Zhou, J., Wang, L., Wang, J., et al. Paeoniflorin and albiflorin attenuate neuropathic pain via MAPK pathway in chronic constriction injury rats. Evid. Based Complement. Alternat. Med 2016:8082753, (2016).

    3. Wang, Y.-L., Wang, J.-X., Hu, X.-X., et al. Antidepressant-like effects of albiflorin extracted From Radix Paeoniae alba. J. Ethnopharmacol. 179, 9-15 (2016).