An OGG1 inhibitor
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OGG1-IN-O8

Item No. 29769

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4-dichloro-benzo[b]thiophene-2-carboxylic acid, hydrazide
CAS Number
350997-39-6
Molecular Formula
C9H6Cl2N2OS
Formula Weight
261.1
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 5mg/mLDMSO: 10mg/mLDMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
λmax
237, 284, 311 nm
SMILES
ClC1=C(C(Cl)=C(C(NN)=O)S2)C2=CC=C1
InChi Code
InChI=1S/C9H6Cl2N2OS/c10-4-2-1-3-5-6(4)7(11)8(15-5)9(14)13-12/h1-3H,12H2,(H,13,14)
InChi Key
HSSHUDKWJRJKPV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $38

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    5 mg

    $94

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    10 mg

    $165

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    25 mg

    $363

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    Cayman Chemical
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    Product Description

    OGG1-IN-O8 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1; IC50 = 0.35 µM).1 It is selective for OGG1 over Nei-like DNA glycosylase 1 (NEIL1), endonuclease III homolog 1 (NTH1), and formamidopyrimidine DNA glycosylase (Fpg) at 50 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lloyd, R.S., Mccullough, A.K., and Donley, N. Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1). (2016).