An oxadiazole antibiotic
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CAY10742

Item No. 29800

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[3-[4-(4-fluorophenoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-indole
CAS Number
1649473-91-5
Molecular Formula
C22H14FN3O2
Formula Weight
371.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 11 mg/mlDMF:PBS (pH 7.2) (1:2): 0.3 mg/mlDMSO: 10 mg/ml
λmax
262 nm
SMILES
FC(C=C1)=CC=C1OC(C=C2)=CC=C2C3=NOC(C4=CC=C5C(C=CN5)=C4)=N3
InChi Code
InChI=1S/C22H14FN3O2/c23-17-4-8-19(9-5-17)27-18-6-1-14(2-7-18)21-25-22(28-26-21)16-3-10-20-15(13-16)11-12-24-20/h1-13,24H
InChi Key
LJMUZZUGHRTIJT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $49

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    5 mg

    $213

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    10 mg

    $376

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    25 mg

    $820

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    Cayman Chemical
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    Product Description

    CAY10742 is an orally bioavailable oxadiazole antibiotic.1 It is active against the Gram-positive bacteria S. aureus, S. epidermidis, S. haemolyticus, B. cereus, B. licheniformis, E. faecalis, and E. faecium (MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistant S. aureus (MRSA) infection.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  .