An acylhydrazone antifungal
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D13

Item No. 29818

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-bromo-benzoic acid, 2-[(3,5-dibromo-2-hydroxyphenyl)methylene]hydrazide
CAS Number
321945-27-1
Molecular Formula
C14H9Br3N2O2
Formula Weight
476.9
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 10 mg/ml
λmax
244, 295, 307, 341 nm
SMILES
O=C(N/N=C/C1=CC(Br)=CC(Br)=C1O)C2=CC=C(Br)C=C2
InChi Code
InChI=1S/C14H9Br3N2O2/c15-10-3-1-8(2-4-10)14(21)19-18-7-9-5-11(16)6-12(17)13(9)20/h1-7,20H,(H,19,21)/b18-7+
InChi Key
QERLWOMVFDBAFP-CNHKJKLMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $41

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    5 mg

    $128

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    10 mg

    $235

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    25 mg

    $534

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    Cayman Chemical
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    Product Description

    D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrob. Agents Chemother. 62(5), e00156-00118 (2018).