A triterpenoid with diverse biological activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

α-Amyrin

Item No. 29831

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β)-urs-12-en-3-ol
CAS Number
638-95-9
Synonyms
  • NSC 114787
Molecular Formula
C30H50O
Formula Weight
426.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C)[C@@]4([H])[C@@H](C)[C@H](C)CC5
InChi Code
InChI=1S/C30H50O/c1-19-11-14-27(5)17-18-29(7)21(25(27)20(19)2)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h9,19-20,22-25,31H,10-18H2,1-8H3/t19-,20+,22+,23-,24+,25+,27-,28+,29-,30-/m1/s1
InChi Key
FSLPMRQHCOLESF-SFMCKYFRSA-N
Origin
Plant/Burseraceae
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $41

    Add

    5 mg

    $183

    Add

    10 mg

    $324

    Add

    25 mg

    $556

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    α-Amyrin is a triterpenoid that has been found in B. copallifera and has diverse biological activities.1,2,3,4 It inhibits HIV-1 reverse transcriptase (IC50 = 3.3 µM).1 α-Amyrin inhibits the proliferation of B16 2F2 melanoma cells and LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages (IC50s = 50 and 8.98 µM, respectively).2,3 It reduces myeloperoxidase (MPO) activity, indicating a decrease in polymorphonuclear leukocyte (PMN) infiltration, and ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ID50s = 0.45 and 0.31 mg/ear, respectively).4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Akihisa, T., Ogihara, J., Kato, J., et al. Inhibitory effects of triterpenoids and sterols on human immunodeficiency virus-1 reverse transcriptase. Lipids 36(5), 507-512 (2001).

    2. Hata, K., Hori, K., and Takahashi, S. Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line. J. Nat. Prod. 65(5), 645-648 (2002).

    3. Romero-Estrada, A., Maldonado-Magaña, A., González-Christen, J., et al. Anti-inflammatory and antioxidative effects of six pentacyclic triterpenes isolated from the Mexican copal resin of Bursera copallifera. BMC Complement. Altern. Med. 16(1), 422 (2016).

    4. Otuki, M.F., Vieira-Lima, F., Malheiros, Â., et al. Topical antiinflammatory effects of the ether extract from Protium kleinii and α-amyrin pentacyclic triterpene. Eur. J. Pharmacol. 507(1-3), 253-259 (2005).