An Analytical Reference Standard
Related Products
Enantiomer(s)
31565(S)-Modafinil
Isomer(s)
15417Modafinil
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(R)-Modafinil

Item No. 29910

Restricted Product (Schedule IV)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • CEP-10952
  • CRL 40982
  • (-)-Modafinil
Technical Information
Formal Name
2-[(R)-(diphenylmethyl)sulfinyl]-acetamide
CAS Number
112111-43-0
Molecular Formula
C15H15NO2S
Formula Weight
273.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 0.25 mg/ml
SMILES
O=[S@](CC(N)=O)C(C1=CC=CC=C1)C2=CC=CC=C2
InChi Code
InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)/t19-/m1/s1
InChi Key
YFGHCGITMMYXAQ-LJQANCHMSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (R)-Modafinil (Item No. 29910) is an analytical reference standard categorized as a nootropic and stimulant.1,2,3 (R)-Modafinil substitutes for cocaine (Item Nos. ISO60176 | 16186 | 22165) in a two-lever drug discrimination test. Formulations containing (R)-modafinil have been used in the treatment of narcolepsy, obstructive sleep apnea, and shift work disorder. (R)-Modafinil is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Loland, C.J., Mereu, M., Okunola, O.M., et al. R-Modafinil (armodafinil): A unique dopamine uptake inhibitor and potential medication for psychostimulant abuse. Biol. Psychiatry 72(5), 405-413 (2012).

    2. Schmitt, K.C., and Reith, M.E.A. The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. PLoS One 6(10), e25790 (2011).

    3. Czeisler, C.A., Walsh, J.K., Wesnes, K.A., et al. Armodafinil for treatment of excessive sleepiness associated with shift work disorder: A randomized controlled study. Mayo Clin. Proc. 84(11), 958-972 (2009).