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Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola.1 It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC50 = 89 μM).2 Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC50 = 38.4 μM).3,2
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1. Cyperine, a phytotoxin produced by Ascochyta cypericola, a fungal pathogen of Cyperus rotundus. Phytochemistry 30(7), 2191-2192 (1991).
2. A pathogenic fungi diphenyl ether phytotoxin targets plant enoyl (acyl carrier protein) reductase. Plant Physiol. 174(3), 1062-1071 (2008).
3. Phytotoxic metabolites of Phoma sorghina, a new foliar pathogen of pokeweed. Mycologia 84(5), 715-723 (1992).