A vitamin B6 analog and an inhibitor of S1P lyase
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

4-Deoxypyridoxine Phosphate

Item No. 29973

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-hydroxy-4,6-dimethyl-3-pyridinemethanol, 3-(dihydrogen phosphate)
CAS Number
883-84-1
Synonyms
  • 4-Deoxypyridoxine Phosphate
  • DOP-P
  • DOP Phosphate
  • NSC 29870
Molecular Formula
C8H12NO5P
Formula Weight
233.2
Purity
≥90%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Water: soluble
λmax
283 nm
SMILES
CC1=NC=C(COP(O)(O)=O)C(C)=C1O
InChi Code
InChI=1S/C8H12NO5P/c1-5-7(4-14-15(11,12)13)3-9-6(2)8(5)10/h3,10H,4H2,1-2H3,(H2,11,12,13)
InChi Key
RBCOYOYDYNXAFA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $36

    Add

    5 mg

    $128

    Add

    10 mg

    $236

    Add

    25 mg

    $502

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.1 It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = <1 and >100 µM in the absence and presence of vitamin B6, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ohtoyo, M., Tamura, M., Machinaga, N., et al. Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levels. Lipids 51(10), 1207-1216 (2016).