A nonionic surfactant
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Dodecanoyl D-Sucrose

Item No. 29982

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
β-D-fructofuranosyl, α-D-glucopyranoside, monododecanoate
CAS Number
25339-99-5
Synonyms
  • Sucrose monolaurate
Molecular Formula
C24H44O12
Formula Weight
524.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 15 mg/mlDMSO: 5 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 3 mg/ml
SMILES
O[C@@H]1[C@@H](COC(CCCCCCCCCCC)=O)O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O
InChi Code
InChI=1S/C24H44O12/c1-2-3-4-5-6-7-8-9-10-11-17(27)33-13-16-18(28)20(30)21(31)23(34-16)36-24(14-26)22(32)19(29)15(12-25)35-24/h15-16,18-23,25-26,28-32H,2-14H2,1H3/t15-,16-,18-,19-,20+,21-,22+,23-,24+/m1/s1
InChi Key
KGUHOFWIXKIURA-VQXBOQCVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

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    Product Description

    Dodecanoyl D-sucrose is a nonionic surfactant.1 It is active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay when used at a concentration of 255 mM. Transcutaneous immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to immunization with uncoated ovalbumin.2 Topical administration of a dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel.3 Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhao, L., Zhang, H., Hao, T., et al. In vitro antibacterial activities and mechanism of sugar fatty acid esters against five food-related bacteria. Food Chem. 187, 370-377 (2015).

    2. Kitaoka, M., Imamura, K., Hirakawa, Y., et al. Sucrose laurate-enhanced transcutaneous immunization with a solid-in-oil nanodispersion. MedChemComm. 5(1), 20-24 (2014).

    3. Vermeire, A., De Muynck, C., Vandenbossche, G., et al. Sucrose laurate gels as a percutaneous delivery system for oestradiol in rabbits. J. Pharm. Pharmacol. 48(5), 463-467 (1996).

    4. Zhang, X., Wei, W., Cao, X., et al. Characterization of enzymatically prepared sugar medium-chain fatty acid monoesters. J. Sci. Food Agric. 95(8), 1631-1637 (2015).