A bacterial metabolite
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IT-143A

Item No. 30044

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(10-hydroxy-3,5,7,9,11,13-hexamethyl-2,5,7,11,13-pentadecapentaenyl)-5,6-dimethoxy-3-methyl-4-pyridinol
CAS Number
183485-32-7
Molecular Formula
C29H43NO4
Formula Weight
469.7
Purity
≥95%
Formulation (Request formulation change)
An oil
SMILES
OC1=C(C)C(C/C=C(C)/C/C(C)=C/C(C)=C/C(C)C(O)/C(C)=C/C(C)=C/C)=NC(OC)=C1OC
InChi Code
InChI=1S/C29H43NO4/c1-11-18(2)16-22(6)26(31)23(7)17-21(5)15-20(4)14-19(3)12-13-25-24(8)27(32)28(33-9)29(30-25)34-10/h11-12,15-17,23,26,31H,13-14H2,1-10H3,(H,30,32)/b18-11+,19-12+,20-15+,21-17+,22-16+
InChi Key
UIUDUFUTTXCNJT-RJPZUDLQSA-N
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    Product Description

    IT-143A is a bacterial metabolite originally isolated from Streptomyces sp. IT-143.1 It is active against the bacterium M. luteus (MIC = 6.25 μg/ml) and the fungi A. fumigatus and T. rubrum in vitro (MICs = 12.5-25 μg/ml).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Urakawa, A., Sasaki, T., Yoshida, K., et al. IT-143-A and B, novel piericidin-group antibiotics produced by Streptomyces Sp. J. Antibiot. (Tokyo) 49(10), 1052-1055 (1996).