A lipidated amino acid
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Myristoyl Glycine

Item No. 30107

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(1-oxotetradecyl)-glycine
CAS Number
14246-55-0
Synonyms
  • N-Myristoyl-glycine
  • Myristoyl-Gly-OH
  • NSC 622050
  • N-Tetradecanoyl-glycine
Molecular Formula
C16H31NO3
Formula Weight
285.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 0.5 mg/ml
SMILES
CCCCCCCCCCCCCC(NCC(O)=O)=O
InChi Code
InChI=1S/C16H31NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(19)20/h2-14H2,1H3,(H,17,18)(H,19,20)
InChi Key
DYUGTPXLDJQBRB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $79

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    5 mg

    $127

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    10 mg

    $231

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    25 mg

    $421

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    Product Description

    Myristoyl glycine is a lipidated amino acid and fatty amide and an endogenous metabolite.1 It induces browning of human Simpson-Golabi-Behmel syndrome (SGBS) preadipocytes when used at concentrations ranging from 0.0001 to 20 µM. Myristoyl glycine has been used as an immunogen to raise antibodies against myristoylated proteins and as a synthetic intermediate in the synthesis of lipopeptides.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Guijas, C., To, A., Montenegro-Burke, J.R., et al. Drug-initiated activity metabolomics identifies myristoylglycine as a potent endogenous metabolite for human brown fat differentiation. Metabolites 12(8), 749 (2022).

    2. Shoji, S., Tashiro, A., Takenaka, O., et al. Antibodies to an NH2-terminal myristoyl glycine moiety can detect NH2-terminal myristoylated proteins in the retrovirus-infected cells. Biochem. Biophys. Res. Commun. 162(2), 724-732 (1989).

    3. Cotté, A., Bader, B., Kuhlmann, J., et al. Synthesis of the N-terminal lipohexapeptide of human GαO-protein and fluorescent-labeled analogues for biological studies. Chem. Eur. J. 5(3), 922-936 (1999).