A synthetic diterpene
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16-Oxokahweol

Item No. 30117

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3bS,5aS,8R,10aR,10bS)-3b,4,5,8,9,10,10a,10b-octahydro-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7(6H)-one
CAS Number
108664-99-9
Molecular Formula
C19H22O2
Formula Weight
282.4
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: soluble
λmax
287 nm
SMILES
O=C1[C@](C2)([H])CC[C@@]3([H])[C@]4(C)C=CC5=C(C=CO5)[C@@]4([H])CC[C@]32C1
InChi Code
InChI=1S/C19H22O2/c1-18-7-5-16-13(6-9-21-16)14(18)4-8-19-10-12(15(20)11-19)2-3-17(18)19/h5-7,9,12,14,17H,2-4,8,10-11H2,1H3/t12-,14-,17+,18-,19+/m1/s1
InChi Key
ZUHATORLUREVSD-MMSQRJJHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $65

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    5 mg

    $203

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    10 mg

    $340

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    Product Description

    16-Oxokahweol is a synthetic diterpene and derivative of kahweol (Item No. 14015).1 It increases cytosolic glutathione S-transferase (GST) activity and acid-soluble sulfhydryl levels in mouse liver and small bowel mucosa when administered at a dose of 10 µmol/animal once per day for three days.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lam, L.K., Sparnins, V.L., and Wattenberg, L.W. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J. Med. Chem. 30(8), 1399-1403 (1987).