A synthetic non-steroidal estrogen
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Chlorotrianisene

Item No. 30361

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,1′,1′′-(1-chloro-1-ethenyl-2-ylidene)tris[4-methoxy-benzene
CAS Number
569-57-3
Synonyms
  • NSC 10108
  • TACE
  • Tri-p-anisylchloroethylene
Molecular Formula
C23H21ClO3
Formula Weight
380.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
248, 304 nm
SMILES
COC1=CC=C(/C(C2=CC=C(OC)C=C2)=C(Cl)/C3=CC=C(OC)C=C3)C=C1
InChi Code
InChI=1S/C23H21ClO3/c1-25-19-10-4-16(5-11-19)22(17-6-12-20(26-2)13-7-17)23(24)18-8-14-21(27-3)15-9-18/h4-15H,1-3H3
InChi Key
BFPSDSIWYFKGBC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $41

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    1 mg

    $75

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    5 mg

    $255

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    Product Description

    Chlorotrianisene (TACE) is a synthetic non-steroidal estrogen.1,2 In vivo, TACE (5 mg/animal, s.c.) prevents mammary tumor formation induced by demethylbenz[a]anthracene (DMBA) in rats.1 It also prevents bone loss and uterine atrophy in ovariectomized rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kellen, J.A. Suppression of DMBA [7,12-dimethylbenz(a)anthracene] tumor induction in rat mammary glands by pregnancy or chlorotrianisene. Z. Krebsforsch. 79(2), 75-77 (1973).

    2. Zhang, J., Yang, W., and Shen, Z. Prevention of bone loss by chlorotrianisene in oophorectomized rats. Zhonghua Fu Chan Ke Za Zhi 32(9), 535-537 (1997).