A phenylpropanoid glycoside with diverse biological activities
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Coniferin

Item No. 30364

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
β-glucopyranoside, 4-(3-hydroxy-1-propen-1-yl)-2-methoxyphenyl
CAS Number
531-29-3
Synonyms
  • Abietin
Molecular Formula
C16H22O8
Formula Weight
342.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 10 mM
SMILES
COC1=CC(/C=C/CO)=CC=C1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
InChi Code
InChI=1S/C16H22O8/c1-22-11-7-9(3-2-6-17)4-5-10(11)23-16-15(21)14(20)13(19)12(8-18)24-16/h2-5,7,12-21H,6,8H2,1H3/b3-2+/t12-,13-,14+,15-,16-/m1/s1
InChi Key
SFLMUHDGSQZDOW-FAOXUISGSA-N
Origin
Plant/Typhonium giganteum Engl.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $134

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    1 mg

    $253

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    5 mg

    $795

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    Product Description

    Coniferin is a phenylpropanoid glycoside and a lignan precursor that has been found in V. album and has diverse biological activities.1,2,3 It inhibits ADP-induced platelet aggregation in isolated human platelet-rich plasma when used at concentrations ranging from 0.01 to 1 µM.1 Coniferin has antioxidant activity in an oxygen radical absorbance capacity (ORAC) assay.2 It induces contractions in isolated rat aortic rings when used at concentrations ranging from 0.001 to 1 mM.3 In vivo, coniferin (1 mg/kg) increases blood pressure in spontaneously hypertensive rats.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Panossian, A., Kocharian, A., Matinian, K., et al. Pharmacological activity of phenylpropanoids of the mistletoe, Viscum album L., host: Pyrus caucasica Fed. Phytomedicine 5(1), 11-17 (1998).

    2. Kayano, S., Kikuzaki, H., Ikami, T., et al. A new bipyrrole and some phenolic constituents in prunes (Prunus domestica L.) and their oxygen radical absorbance capacity (ORAC). Biosci. Biotechnol. Biochem. 68(4), 942-944 (2004).

    3. Deliorman, D., Çaliş, İ., Ergun, F., et al. Studies on the vascular effects of the fractions and phenolic compounds isolated from Viscum album ssp. album. J. Ethnopharmacol. 72(1-2), 323-329 (2000).

    4. Sawabe, A., Kumamoto, H., and Matsubara, Y. Bioactive glycosides in citrus fruit peels. Bull. Inst. Compr. Agr. Sci. Kinki Univ. 6, 57-67 (1998).