A racemic mixture of D-threo-isocitric acid and L-threo-isocitric acid
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Product Categories

Product Type

Biochemicals

Research Area

Endocrinology & Metabolism
Carbohydrate Metabolism

DL-threo-Isocitric Acid (sodium salt hydrate)

Item No. 30378

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-carboxy-2,3-dideoxy-threo-pentaric acid, trisodium salt, hydrate
Molecular Formula
C6H5O7 • 3Na [XH2O]
Formula Weight
258.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 5mg/mL
SMILES
[O-]C(C[C@@H](C([O-])=O)[C@H](O)C([O-])=O)=O.[Na+].[Na+].[Na+].O
InChi Code
InChI=1S/C6H8O7.3Na.H2O/c7-3(8)1-2(5(10)11)4(9)6(12)13;;;;/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13);;;;1H2/q;3*+1;/p-3/t2-,4+;;;;/m1..../s1
InChi Key
BPEHKAXIRZOKIS-AEYVVBJPSA-K
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 mg

    $50

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    1 g

    $95

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    Product Description

    DL-threo-Isocitric acid is a racemic mixture of D-threo-isocitric acid and L-threo-isocitric acid. It has been used as a substrate to measure the activity of yeast isocitrate lyase in C. albicans, S. cerevisiae, or K. lactis cell-free extracts.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Koivistoinen, O.M., Kuivanen, J., Barth, D., et al. Glycolic acid production in the engineered yeasts Saccharomyces cerevisiae and Kluyveromyces lactis. Microb. Cell Fact. 12, 82 (2013).

    2. Ansari, M.A., Fatima, Z., Ahmad, K., et al. Monoterpenoid perillyl alcohol impairs metabolic flexibility of Candida albicans by inhibiting glyoxylate cycle. Biochem. Biophys. Res. Commun. 495(1), 560-566 (2018).