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Oleyl alcohol is a monounsaturated fatty alcohol produced by the reduction of oleic acid (Item Nos. 90260 | 24659).1 Topical application of an oleyl alcohol (5% w/w), propylene glycol, and Carbopol® 940 gel containing the non-steroidal anti-inflammatory drug (NSAID) piroxicam (Item No. 13368) enhances piroxicam absorption into isolated rat abdominal skin compared to a control gel not containing oleyl alcohol.2 Oleyl alcohol also increases naloxone penetration into isolated postmortem human skin when applied at a 10% concentration.3
WARNING This product is not for human or veterinary use.
1. Oleyl alcohol from animal fats by catalytic reduction. J. Am. Oil Chem. Soc. 47, 326-328 (1970).
2. Penetration enhancer effects on the in vitro percutaneous absorption of piroxicam through rat skin. Int. J. Pharm. 117(2), 219-224 (1995).
3. Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides. Int. J. Pharm. 33(1-3), 225-234 (1986).