An amine-reactive fluorescent probe
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Cy2-SE

Item No. 30394

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[3-[3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-2(3H)-benzoxazolylidene]-1-propen-1-yl]-3-ethyl-benzoxazolium, monoiodide
CAS Number
186205-33-4
Synonyms
  • Cy2 NHS Ester
  • N-hydroxysuccinimidyl Ester Cy2
Molecular Formula
C29H30N3O6 • I
Formula Weight
643.5
Purity
≥98%
Emission
510 nm
Excitation
473 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:1): 0.50 mg/mlDMSO: 10 mg/mlEthanol: slightly solublePBS (pH 7.2): slightly soluble
λmax
486 nm
SMILES
O=C(ON1C(CCC1=O)=O)CCCCCN2/C(OC3=CC=CC=C32)=C/C=C/C4=[N+](CC)C5=CC=CC=C5O4.[I-]
InChi Code
InChI=1S/C29H30N3O6.HI/c1-2-30-21-11-5-7-13-23(21)36-27(30)15-10-16-28-31(22-12-6-8-14-24(22)37-28)20-9-3-4-17-29(35)38-32-25(33)18-19-26(32)34;/h5-8,10-16H,2-4,9,17-20H2,1H3;1H/q+1;/p-1
InChi Key
RQYPAAVMQSMNBY-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $49

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    5 mg

    $202

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    10 mg

    $354

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    25 mg

    $762

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    Product Description

    Cy2-SE is an amine-reactive fluorescent probe.1 It has commonly been used to label proteins.1,2 Cy2-SE displays excitation/emission maxima of 473/510 nm, respectively.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Coombs, K.M. Update on proteomic approaches to uncovering virus-induced protein alterations and virus-host protein interactions during the progression of viral infection. Expert Rev. Proteomics 17(7-8), 513-532 (2020).

    2. Park, H., Ha, J., Koo, J.Y., et al. Label-free target identification using in-gel fluorescence difference via thermal stability shift. Chem. Sci. 8(2), 1127-1133 (2017).

    3. Nikolić, A., Perić, M., Ladouce, R., et al. Death by UVC light correlates with protein damage in isogenic human tumor cells: Primary tumor SW480 versus its metastasis SW620. J. Proteomics Computational Biol. 2(1), 1-12 (2016).