A non-androgenic steroid
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4-Androsten-11β-ol-3,17-dione

Item No. 30410

Technical Information
Formal Name
(11β)-11-hydroxy-androst-4-ene-3,17-dione
CAS Number
382-44-5
Synonyms
  • NSC 12168
  • 11β-Hydroxy-4-androsten-3,17-dione
  • NSC 17102
  • 11OHA4
  • U-2826
Molecular Formula
C19H26O3
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 20mg/mLDMF:PBS (pH 7.2) (1:6): 0.14mg/mLDMSO: 15mg/mLEthanol: 5mg/mL
λmax
241 nm
SMILES
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CCC4=O)=C1
InChi Code
InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1
InChi Key
WSCUHXPGYUMQEX-KCZNZURUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    4-Androsten-11β-ol-3,17-dione (11OHA4) is a steroid that has been found in isolated human female adrenal veins.1 It is non-androgenic, however, it is metabolized to the androgenic 5α-reduced C19 steroids 11-hydroxy-5α-androstanedione, 11-keto-5α-androstanedione, 11-hydroxydihydrotestosterone, and 11-ketodihydrotestosterone in LNCaP cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Storbeck, K.-H., Bloem, L.M., Africander, D., et al11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer? Mol. Cell. Endocrinol. 377(1-2), 135-146 (2013).