A cardenolide
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14-Anhydrodigitoxigenin

Item No. 30439

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5β)-3β-hydroxy-carda-14,20(22)-dienolide
CAS Number
4321-20-4
Molecular Formula
C23H32O3
Formula Weight
356.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS (pH 7.2) (1:1): 0.5 mg/mlDMSO: 20 mg/mlEthanol: 5 mg/ml
SMILES
O[C@H]1CC[C@@]2(C)[C@@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)C3=CC[C@]4([H])C(CO5)=CC5=O)([H])C1
InChi Code
InChI=1S/C23H32O3/c1-22-9-7-16(24)12-15(22)3-4-17-19-6-5-18(14-11-21(25)26-13-14)23(19,2)10-8-20(17)22/h6,11,15-18,20,24H,3-5,7-10,12-13H2,1-2H3/t15-,16+,17+,18-,20+,22+,23-/m1/s1
InChi Key
FXWZKNUSMJAEKJ-HHALRHBMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $63

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    10 mg

    $118

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    25 mg

    $242

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    50 mg

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    Product Description

    14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kamano, Y., Tozawa, M., and Pettit, G.R. Steroids and related natural products. 90. 15β-Hydroxydigitoxigenin. The Journal of Organic Chemistry 40(6), 793-796 (1975).

    2. Megges, R., Weiland, J., Schön, R., et al. Cardenamides from cardenolides: Cardiac and anticancer activities. Collect. Czech. Commun. 67(3), 336-352 (2002).