A halogenated form of lauric acid
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12-Bromododecanoic Acid

Item No. 30465

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
73367-80-3
Synonyms
  • 12-Bromo-C12:0
  • 12-Bromododecanoate
  • 12-Bromolauric Acid
  • NSC 660375
Molecular Formula
C12H23BrO2
Formula Weight
279.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/ml
SMILES
BrCCCCCCCCCCCC(O)=O
InChi Code
InChI=1S/C12H23BrO2/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h1-11H2,(H,14,15)
InChi Key
YYKBWYBUCFHYPR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $63

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    500 mg

    $110

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    1 g

    $195

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    Product Description

    12-Bromododecanoic acid is a halogenated form of lauric acid (Item No. 10006626). It has been used in the synthesis of clickable forms of myristic acid (Item No. 13351) and as a model fatty acid ligand to determine the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes.1,2 12-Bromododecanoic acid (10 µg/ml) reduces virion DNA in the culture supernatant of primary hepatocytes isolated from a duckling model of hepatitis B virus (HBV) infection and inhibits HIV replication in CEM-SS T cells (EC50 = 38 µM).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Heal, W.P., Wickramasinghe, S.R., Leatherbarrow, R.J., et al. N-Myristoyl transferase-mediated protein labelling in vivo. Org. Biomol. Chem. 6(13), 2308-2315 (2008).

    2. Qin, B.Y., Creamer, L.K., Baker, E.N., et al. 12-Bromododecanoic acid binds inside the calyx of bovine β-lactoglobulin. FEBS Lett. 438(3), 272-278 (1998).

    3. Parang, K., Wiebe, L.I., Knaus, E.E., et al. In vitro antiviral activities of myristic acid analogs against human immunodeficiency and hepatitis B viruses. Antiviral Res. 34(3), 75-90 (1997).